Search for and download brochures, application notes, presentations and posters.
Read our Blog!
Search here for recent application notes from Anatune and our partners.
We organise our own events and attend many others.

We love to talk with our customers face-to-face so, if you are attending an event, let us know and we can arrange to meet.
Lunch & Learn seminars are provided free by Anatune and consist of one-hour sessions, conducted by experienced analytical chemists, covering topics that are relevant to the work you do.
Download copies of recent presentations given by the Anatune team.
Here you can download copies of recent posters presented by the Anatune team and our partners.
Who we are, what we do and what we believe is important.
We recognise that data quality, analytical flexibility and effective support should be our primary concern and Anatune is dedicated to delivering these benefits to analysts in the UK and Ireland.
Our first priority is to maintain a great team spirit and we only employ people with great attitudes.

We believe in continual learning and personal development. We train our staff well.

Find out more about them here.
Our role is to bring the World's best analytical technologies to laboratories in the UK and Ireland.

We do this in partnership with some great companies.
We do our best work and achieve the very best outcomes when collaborating with our customers.
We have built strong, long-term relationships with customers resulting in repeat business and an unbeatable reputation for reliability and trust.

Here's what they say about us...
While it’s certainly not our primary motivation, peer recognition is important to us. See our latest and greatest achievements here.

High-Throughput Residual Solvent and Residual Monomer Analysis Using Selected Ion Flow Tube Mass Spectrometry (SIFT-MS)

Application Note

Residual solvent and monomer testing are analyses that are widely conducted in the pharmaceutical and food industries to comply with regulations and ensure the quality and safety of the final products.

Currently, the most widely used methods for this type of analyses are chromatographic. However, these can be slow, and often require extensive sample preparation and derivatisation prior to injection. A number of different methods may be required to cover the necessary range of compounds. Whilst formaldehyde can be difficult to analyse using gas chromatography, a SIFT-MS approach removes the need for any derivatisation and the speed with which SIFT-MS analyses a sample can greatly increase throughput. A number of compounds were analysed simultaneously including challenging species such as ammonia and formaldehyde alongside solvents such as benzene and toluene. All 13 compounds were monitored in 90 seconds.

Questions can also be asked regarding the total amount of a given monomer that is present in the final solid product (rather than from a single measurement of headspace).  SIFT-MS coupled to an autosampler can answer this question quickly using multiple headspace extraction. This application note demonstrates the ability of SIFT-MS to provide rapid, mass-screening of products for residual solvents would could significantly improve QA/QC processes in the pharmaceutical industry. This approach could potentially be implemented on an existing conveyor system, contributing to the strive towards continuous manufacturing processes.

Application Note Downloads

High-Throughput Residual Solvent and Residual Monomer Analysis Using Selected Ion Flow Tube Mass Spectrometry


Leave a Reply

Your email address will not be published. Required fields are marked *

Time limit is exhausted. Please reload CAPTCHA.